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New perspective on the natural course of chronic HBV infection

Yong-Yuan Zhang,Ke-Qin Hu,Zhongping Duan

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 129-134 doi: 10.1007/s11684-014-0339-x

Abstract:

Chronic hepatitis B virus (HBV) infection is a significant threat to public health and an enormousMechanisms responsible for chronic HBV infection remain poorly understood.Natural course of chronic HBV infection is conventionally viewed as an uninterrupted process that isHBV infection.and reinfection, and such cycles prolong the chronic HBV infection course.

Keywords： hepatitis B virus     chronic HBV infection     natural course     hepatitis B     seroconversion    

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Current recommendations of managing HBV infection in preconception or pregnancy

James S. Park,Calvin Pan

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 158-165 doi: 10.1007/s11684-014-0340-4

Abstract: Management of chronic hepatitis B during pregnancy is challenging.occurs perinatally although immunoprophylaxis is widely available for infants born to mothers with chronichepatitis B infection.In this article, we will review the features of hepatitis B infection before, during and after the pregnancy

Keywords： antiviral therapy     Caesarean section     cirrhosis     hepatitis B     immunoprophylaxis     mother-to-child transmission     pregnancy     prevention    

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Potential use of serum HBV RNA in antiviral therapy for chronic hepatitis B in the era of nucleos(t)ide

Fengmin Lu, Jie Wang, Xiangmei Chen, Dongping Xu, Ningshao Xia

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 502-508 doi: 10.1007/s11684-017-0590-z

Abstract:

Although the efficacy of nucleos(t)ide analogue (NA) has been confirmed for treatment of chronic hepatitiscycle of HBV replication, and the potential significance of serum HBV RNA is systematically describedThe production of HBV RNA virion-like particles should not be blocked by NA; in this regard, serum HBVTherefore, the concept of virological response is redefined as persistent loss of serum HBV DNA and HBVimplicated as a “para-functional cure,” a status nearly close to the functional cure of chronic

Keywords： chronic hepatitis B     serum HBV RNA     nucleos(t)ide analogs     virological response     para-functional cure    

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Chronic hepatitis B virus infection: epidemiology, prevention, and treatment in China

Rui Yu,Rong Fan,Jinlin Hou

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 135-144 doi: 10.1007/s11684-014-0331-5

Abstract:

Chronic hepatitis B is a major health problem in China.The universal vaccination program since 1992 has changed the epidemiology of hepatitis B virus infectionChronic hepatitis B poses a heavy burden to the society in China.

Keywords： chronic hepatitis B     epidemiology     prevention     treatment    

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Current hepatitis B treatment guidelines and future research directions

Jonathan Skupsky,Ke-Qin Hu

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 145-157 doi: 10.1007/s11684-014-0335-1

Abstract:

Hepatitis B virus (HBV) infection causes a tremendous clinical burden across the world with more thanhalf a million people dying annually from HBV related disease.Significant advances have been made in HBV treatment in the past decade and several guidelines have beenAlthough these recommendations have been valuable to help optimize HBV treatment, there is discordancein treatment criteria and many patients infected with HBV may fall outside of these recommendations.

Keywords： chronic hepatitis B     HBV treatment guidelines     APASL guidelines     EASL guidelines     AASLD guidelines    

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Impact of HBV replication in peripheral blood mononuclear cell on HBV intrauterine transmission

Xiaohong Shi, Xuefei Wang, Xixi Xu, Yongliang Feng, Shuzhen Li, Shuying Feng, Bo Wang, Suping Wang

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 548-553 doi: 10.1007/s11684-017-0597-5

Abstract: cell (PBMC) from HBsAg-positive mothers on HBV intrauterine transmission.Within 24 h after birth, HBV serological markers, serum HBV DNA, PBMC HBV relaxed circular DNA (rcDNAThe relationship between HBV replication in PBMC and HBV intrauterine transmission was examined throughMaternal PBMC HBV cccDNA was a risk factor of HBV intrauterine transmission (OR= 6.003, 95% CI: 1.249&plays a critical role in HBV intrauterine transmission.

Keywords： PBMC     HBV cccDNA     HBV rcDNA     HBV intrauterine transmission    

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Cyclooxygenase-2 gene-1195G/A genotype is associated with the risk of HBV-induced HCC: A case-control

Li-Feng LIU MD, PhD, Qiong CHEN MD, PhD, Ying CHANG MD, PhD, Ju-Sheng LIN MD, PhD, Jin-Liang ZHANG MM,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 90-95 doi: 10.1007/s11684-010-0021-x

Abstract: evaluate their effects on the risk of primary hepatocellular carcinoma (HCC) with hepatitis B virus (HBV) infection.Subjects included primary HCC patients with HBV infection (=210), chronic hepatitis B cases (=210) andWe found-1195A allele carriers had a higher risk of HCC with HBV infection (OR, 0.72; 95% CI, 0.548–The-1195A allele might be used as a marker in screening individuals at high risk of HCC with HBV infection

Keywords： gene     single nucleotide polymorphisms     susceptibility     primary hepatocellular carcinoma     hepatitis B virus infection    

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A Resilience Approach for Diagnosing and Predicting HBV-Related Diseases based on Blood Tests Article

Gege Hou,Yunru Chen,Xiaojing Liu,Dong Zhang,Zhimin Geng,Shubin Si

Engineering 2024, Volume 32, Issue 1,   Pages 174-185 doi: 10.1016/j.eng.2023.06.013

Abstract:

Chronic hepatitis B virus (HBV) infection, which threatens global publicExaminations for liver diseases related to chronic HBV infection—including laboratory tests, ultrasoundsestablish an economical and effective diagnosis method in order to streamline the medical process for HBV-related

Keywords： HBV-related diseases     Functional resilience     Improve medical resource utilization     Critical states     Network    

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Effect of renal function and hemodialysis on the serum tumor markers in patients with chronic kidney

YU Xiaofang, XU Xialian, YE Zhibin

Frontiers of Medicine 2007, Volume 1, Issue 3,   Pages 308-311 doi: 10.1007/s11684-007-0059-6

Abstract: In patients with chronic renal failure, whether they have had hemodialysis or not, the specificity ofIt has been recently shown that some tumor markers are higher in patients with chronic kidney diseaseThe 232 non-dialysis patients with CKD and 37 chronic uremic patients treated with maintenance hemodialysis

Keywords： CKD     non-dialysis     valuable     detection     chronic    

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Acupuncture is ineffective for chronic low back pain? A critical analysis and rethinking

Xuqiang Wei, Baoyan Liu

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 767-775 doi: 10.1007/s11684-020-0785-6

Abstract: Most RCTs conclude that acupuncture procedures for chronic low back pain (CLBP) had no significant difference

Keywords： chronic low back pain     sham acupuncture     acupuncture     methodology     therapeutic evaluation    

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Eliminating mother-to-child transmission of HBV: progress and challenges in China

Wenzhan Jing, Jue Liu, Min Liu

Frontiers of Medicine 2020, Volume 14, Issue 1,   Pages 21-29 doi: 10.1007/s11684-020-0744-2

Abstract: China has the world’s largest burden of hepatitis B virus (HBV) infection, but the country has made considerableStudies on the optimal antiviral treatment regimen for pregnant women with high HBV-DNA load have alsoHowever, China still faces challenges in eliminating MTCT of HBV.than that of the national level because of limited health resources and public health education for HBVIntegration of current services to prevent MTCT of HBV with other relevant health services can increase

Keywords： hepatitis B virus     mother-to-child transmission     progress     challenge    

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Vaccine therapies for chronic hepatitis B: can we go further?

Yumei Wen, Xuanyi Wang, Bin Wang, Zhenhong Yuan

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 17-23 doi: 10.1007/s11684-014-0313-7

Abstract:

Chronic hepatitis B is a major health burden worldwide.progress in antiviral treatment, therapeutic vaccination is a promising new strategy for the control of chronicOn the basis of the major specific and non-specific immune dysregulations and defects in chronic hepatitis

Keywords： chronic hepatitis B     therapeutic     antigen-antibody complexes     DNA     vaccine    

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Perceived resource support for chronic illnesses among diabetics in north-western China

Huiqin Zhong,Ya Shao,Ling Fan,Tangshen Zhong,Lu Ren,Yan Wang

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 219-227 doi: 10.1007/s11684-016-0441-3

Abstract: study aims to analyze support from multiple and multilevel sources for diabetic patients by using the ChronicFactors affecting the utilization of chronic illness resources were determined through univariate analysis297 diabetic patients surveyed, 67% failed to reach the standard (more than 3 points) of utilizing chronicImproved utilization of chronic illness resources was conducive for proper diabetes self-management.Furthermore, the level of utilization of chronic illness resources increased with age, literacy level

Keywords： chronic illness resources survey     diabetes     community     north-western China    

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INTERFERENCE BY NON-HOST PLANT ROOTS AND ROOT EXUDATES IN THE INFECTION PROCESSES OF PHYTOPHTHORA NICOTIANAE

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 3,   Pages 447-459 doi: 10.15302/J-FASE-2021399

Abstract: N-formylpiperidine were consistently identified in the fennel rhizosphere and were found to interfere with the infectionbetween non-host roots and pathogens were found to be an important factor in the inhibition by fennel of infection

Keywords： fennel and tobacco rotation     infection behavior     Phytophthora nicotianae     reactive oxygen species    

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Correlation between viral load and liver cirrhosis in chronic hepatitis B patients

Lili LIU MM , Jiyao WANG MD , Weimin SHE MM ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 271-276 doi: 10.1007/s11684-009-0054-1

Abstract: The aim of this paper is to investigate the relationship between hepatitis B virus (HBV) DNA levels duringthe course and the progression to cirrhosis with chronic hepatitis B.A total of 239 chronic hepatitis B patients confirmed by liver biopsy between 2001 and 2007 were followedHowever, there was no significant difference in cirrhosis progression between different HBV-DNA groupsProgression to cirrhosis in chronic hepatitis B patients is correlated with HBV-DNA levels during follow-up

Keywords： hepatitis B     chronic     viral load     liver cirrhosis    

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Title Author Date Type Operation

New perspective on the natural course of chronic HBV infection

Yong-Yuan Zhang,Ke-Qin Hu,Zhongping Duan

Journal Article

Current recommendations of managing HBV infection in preconception or pregnancy

James S. Park,Calvin Pan

Journal Article

Potential use of serum HBV RNA in antiviral therapy for chronic hepatitis B in the era of nucleos(t)ide

Fengmin Lu, Jie Wang, Xiangmei Chen, Dongping Xu, Ningshao Xia

Journal Article

Chronic hepatitis B virus infection: epidemiology, prevention, and treatment in China

Rui Yu,Rong Fan,Jinlin Hou

Journal Article

Current hepatitis B treatment guidelines and future research directions

Jonathan Skupsky,Ke-Qin Hu

Journal Article

Impact of HBV replication in peripheral blood mononuclear cell on HBV intrauterine transmission

Xiaohong Shi, Xuefei Wang, Xixi Xu, Yongliang Feng, Shuzhen Li, Shuying Feng, Bo Wang, Suping Wang

Journal Article

Cyclooxygenase-2 gene-1195G/A genotype is associated with the risk of HBV-induced HCC: A case-control

Li-Feng LIU MD, PhD, Qiong CHEN MD, PhD, Ying CHANG MD, PhD, Ju-Sheng LIN MD, PhD, Jin-Liang ZHANG MM,

Journal Article

A Resilience Approach for Diagnosing and Predicting HBV-Related Diseases based on Blood Tests

Gege Hou,Yunru Chen,Xiaojing Liu,Dong Zhang,Zhimin Geng,Shubin Si

Journal Article

Effect of renal function and hemodialysis on the serum tumor markers in patients with chronic kidney

YU Xiaofang, XU Xialian, YE Zhibin

Journal Article

Acupuncture is ineffective for chronic low back pain? A critical analysis and rethinking

Xuqiang Wei, Baoyan Liu

Journal Article

Eliminating mother-to-child transmission of HBV: progress and challenges in China

Wenzhan Jing, Jue Liu, Min Liu

Journal Article

Vaccine therapies for chronic hepatitis B: can we go further?

Yumei Wen, Xuanyi Wang, Bin Wang, Zhenhong Yuan

Journal Article

Perceived resource support for chronic illnesses among diabetics in north-western China

Huiqin Zhong,Ya Shao,Ling Fan,Tangshen Zhong,Lu Ren,Yan Wang

Journal Article

INTERFERENCE BY NON-HOST PLANT ROOTS AND ROOT EXUDATES IN THE INFECTION PROCESSES OF PHYTOPHTHORA NICOTIANAE

Journal Article

Correlation between viral load and liver cirrhosis in chronic hepatitis B patients

Lili LIU MM , Jiyao WANG MD , Weimin SHE MM ,

Journal Article